Publications


2023

McVeigh P, McCammick E, Robb E, Brophy P, Morphew RM, Marks NJ, Maule AG (2023). Discovery of long non-coding RNAs in the liver fluke, Fasciola hepatica. bioRxiv.

2022

Herron CM, O'Connor A, Robb E, McCammick E, Hill C, Marks NJ, Robinson MW, Maule AG, McVeigh P (2022). Developmental regulation and functional prediction of microRNAs in an expanded Fasciola hepatica miRNome. Frontiers in Cellular and Infection Microbiology.

Robb E, McCammick E, Wells D, McVeigh P, Gardiner E, Armstrong R, McCusker P, Mousley A, Clarke N, Marks N, Maule AG (2022). Transcriptomic analysis reveals a role for the nervous system in regulating growth and development of Fasciola hepatica juveniles. PLoS Neglected Tropical Diseases.

Davey SD, Chalmers IW, Fernandez-Fuentes N, Swain MT, Smith D, Abbas Abidi SM, Saifullah MK, Raman M, Ravikumar G, McVeigh P, Maule AG, Brophy PM, Morphew RM (2022). In silico characterisation of the complete Ly6 protein family in Fasciola gigantica supported through transcriptomics of the newly-excysted juveniles. Molecular Omics.

Crooks BA, McKenzie D, Cadd LC, McCoy CJ, McVeigh P, Marks NJ, Maule AG, Mousley A, Atkinson LE (2022). Pan-phylum in silico analyses of nematode endocannabinoid signalling systems highlight novel opportunities for parasite drug target discovery. Frontiers in Endocrinology.


2021

Atkinson LE, McCoy CJ, Crooks BA, McKay FM, McVeigh P, McKenzie D, Irvine A, Harrington J, Rosa BA, Mitreva M, Marks NJ, Maule AG, Mousley A (2021). Phylum-spanning neuropeptide GPCR identification and prioritization: Shaping drug target discovery pipelines for nematode parasite control. Frontiers in Endocrinology.


2020

McCusker P, Toet H, Rathinasamy V, Young N, Beddoe T, Anderson G, Dempster R, McVeighP, McCammick E, Wells D, MOusley A, Marks NJ, Maule AG, Spithill TW (2020). Molecular characterisation and vaccine efficacy of two novel developmentally regulated surface tegument proteins of Fasciola hepatica. Veterinary Parasitology.

McCusker P, Hussain W, McVeigh P, McCammick E, Clarke NG, Robb E, McKay FM, Brophy PM, Timson DJ, Mousley A, Marks NJ, Maule AG (2020). RNA interference dynamics in juvenile Fasciola hepatica are altered during in vitro growth and development. International Journal for Parasitology Drugs and Drug Resistance.

McVeigh P (2020). Post-genomic progress in helminth parasitology. Parasitology.

McVeigh P, Maule AG (2020). Can CRISPR help in the fight against parasitic worms? Elife.





McVeigh pre-PI publications

2018

McVeigh P, Cwiklinski K, Garcia-Campos A, Mulcahy G, O'Neill SM, Maule AG, Dalton JP (2018). In silico analyses of protein glycosylating genes in the helminth Fasciola hepatica (liver fluke) predict protein-linked glycan simplicity and reveal temporally dynamic expression profiles. Scientific Reports.

McVeigh P, McCammick E, McCusker P, Wells D, Hodgkinson J, Paterson S, Mousley A, Marks NJ, Maule AG (2018). Profiling G protein-coupled receptors of Fasciola hepatica identifies orphan rhodopsins unique to phylum Platyhelminthes. International Journal for Parasitology Drugs and Drug Resistance.

Hahnel S, Wheeler N, Lu Z, Wangwiwatsin A, McVeigh P, Maule A, Berriman M, Day T, Ribeiro P, Grevelding CG (2018). Tissue-specific transcriptome analyses provide new insights into GPCR signalling in adult Schistosoma mansoni. PLoS Pathogens.

Cwiklinski K, Jewhurst H, McVeigh P, Barbour T, Maule AG, Tort J, O'Neill SM, Robinson MW, Donnelly S, Dalton JP (2018). Infection by the helminth parasite Fasciola hepatica requires rapid regulation of metabolic, virulence, and invasive factors to adjust to its mammalian host. Molecular and Cellular Proteomics.

McVeigh P, McCusker P, Robb E, Wells D, Gardiner E, Mousley A, Marks NJ, Maule AG (2018). Reasons to be nervous about flukicide discovery. Trends in Parasitology.


2016

McCusker P, McVeigh P, Rathinasamy V, Toet H, McCammick E, O'Connor A, Marks NJ, Mousley A, Brennan GP, Halton DW, Spithill TW, Maule AG (2016). Stimulating neoblast-like cell proliferation in juvenile Fasciola hepatica supports growth and progression towards the adult phenotype in vitro. PLoS Neglected Tropical Diseases.

Morphew RM, Wilkinson TJ, Mackintosh N, Jahndel V, Paterson S, McVeigh P, Abbas Abidi SM, Saifullah K, Raman M, Ravikumar G, LaCourse J, Maule A, Brophy PM (2016). Exploring and expanding the fatty-acid-binding protein superfamily in Fasciola species. Journal of Proteome Research.

McCammick EM, McVeigh P, McCusker P, Timson DJ, Morphew RM, Brophy PM, Marks NJ, Mousley A, Maule AG (2016). Calmodulin disruption impacts growth and motility in juvenile liver fluke. Parasites & Vectors.

McVeigh P, McCammick EM, McCusker P, Morphew RM, Mousley A, Abidi A, Saifullah KM, Muthasamy R, Gopalakrishnan R, Spithill TW, Dalton JP, Brophy PM, Marks NJ, Maule AG (2016). RNAi dynamics in juvenile Fasciola spp. liver flukes reveals the persistence of gene silencing in vitro. PLoS Neglected Tropical Diseases.


2014

Shareef PA, Brennan GP, McVeigh P, Khan MA, Morphew RM, Mousley A, Marks NJ, Saifullah MK, Brophy PM, Maule AG, Abidi SM (2014). Time-dependent tegumental surface changes in juvenile Fasciola gigantica in response to triclabendazole treatment in goat. Acta Tropica.

McCoy CJ, Atkinson LE, Zamanian M, McVeigh P, Day TA, Kimber MJ, Marks NJ, Maule AG, Mousley A (2014). New insights into the FLPergic complements of parasitic nematodes: Informing deorphanisation approaches. EuPA Open Proteomics.

Paul S, Alegre KO, Holdsworth SR, Rice M, Brown JA, McVeigh P, Kelly SM, Law CJ (2014). A single-component multidrug transporter of the major facilitator superfamily is part of a network that protects Escherichia coli from bile salt stress. Molecular Microbiology.


2012

Morphew RM, Eccleston N, Wilkinson TJ, McGarry J, Perally S, Prescott M, Ward D, Williams D, Paterson S, Raman M, Ravikumar G, Khalid Saifullah M, Abbas Abidi SM, McVeigh P, Maule AG, Brophy PM, LaCourse EJ (2012). Proteomics and in silico approaches to extend understanding of the glutathione transferase superfamily of the tropical liver fluke Fasciola gigantica. Journal of Proteome Research.

McVeigh P, Atkinson L, Marks NJ, Mousley A, Dalzell JJ, Sluder A, Hammerland L, Maule AG (2012). Parasite neuropeptide biology: Seeding rational drug target selection. International Journal for Parasitology Drugs and Drug Resistance.

Dalzell JJ, Warnock ND, McVeigh P, Marks NJ, Mousley A, Atkinson L, Maule AG (2012). Considering RNAi experimental design in parasitic helminths. Parasitology.

Zamanian M, Agbedanu PN, Wheeler NJ, McVeigh P, Limber MJ, Day TA (2012). Novel RNAi-mediated approach to G protein-coupled receptor deorphanization: proof of principle and characterization of a planarian 5-HT receptor. PLoS One.


2011

Zamanian M, Kimber MJ, McVeigh P, Carlson SA, Maule AG, Day TA (2011). The repertoire of G protein-coupled receptors in the human parasite Schistosoma mansoni and the model organism Schmidtea mediterranea. BMC Genomics.

Maule AG, McVeigh P, Dalzell JJ, Atkinson L, Mousley A, Marks NJ (2011). An eye on RNAi in nematode parasites. Trends in Parasitology.

Kikuchi T, Cotton JA, Dalzell JJ, Hasegawa K, Kanzaki N, McVeigh P, Takanashi T, Tsai IJ, Assefa SA, Cock PJ, Otto TD, Hunt M, Reid AJ, Sanchez-Flores A, Tsuchihara K, Yokoi T, Larsson MC, Miwa J, Maule AG, Sahashi N, Jones JT, Berriman M (2011). Genomic insights into the origin of parasitism in the emerging plant pathogen Bursaphelenchus xylophilus. PLoS Pathogens.

McVeigh P, Mair GR, Novozhilova E, Day A, Zamanian M, Marks NJ, Kimber MJ, Day TA, Maule AG (2011). Schistosome I/Lamides - a new family of bioactive helminth neuropeptides. International Journal for Parasitology.

Dalzell JJ, McVeigh P, Warnock ND, Mitreva M, Bird DM, Abad P, Fleming CC, Day TA, Mousley A, Marks NJ, Maule AG (2011). RNAi effector diversity in nematodes. PLoS Neglected Tropical Diseases.


2010

Atkinson LE, McVeigh P, Kimber MJ, Marks NJ, Eipper BA, Mains RE, Day TA, Maule AG (2010). A PAL for Schistosoma mansoni PHM. Molecular and Biochemical Parasitology.

Johnston MJ, McVeigh P, McMaster S, Fleming CC, Maule AG (2010). FMRFamide-like peptides in root knot nematodes and their potential role in nematode physiology. Journal of Helminthology.

Novozhilova E, Kimber MJ, Qian H, McVeigh P, Robertson AP, Zamanian M, Maule AG, Day TA (2010). FMRFamide-like peptides (FLPs) enhance voltage-gated calcium currents to elicit muscle contraction in the human parasite Schistosoma mansoni. PLoS Neglected Tropical Diseases.

Thornhill J, Kusel J, Oliveira FA, Ribeiro F, Lima SF, Coelho PM, McVeigh P, Mattos AC (2010). Uptake of macromolecules by cercariae during skin penetration and transformation to schistosomula (Schistosoma mansoni). Memorias do Instituto Oswaldo Cruz.

Thornhill JA, McVeigh P, Jurberg AD, Kusel JR (2010). Pathways for the influx of molecules into cercariae of Schistosoma mansoni during skin penetration. Parasitology.


2009

Thornhill J, Coelho PM, McVeigh P, Maule A, Jurberg AD, Kusel JR (2009). Schistosoma mansoni cercariae experience influx of macromolecules during skin penetration. Parasitology.

McVeigh P, Mair GR, Atkinson L, Ladurner P, Zamanian M, Novozhilova E, Marks NJ, Day TA, Maule AG (2009). Discovery of multiple neuropeptide families in the phylum Platyhelminthes. International Journal for Parasitology.

Kusel JR, McVeigh P, Thornhill JA (2009). The schistosome excretory system: a key to regulation of metabolism, drug excretion and host interaction. Trends in Parasitology.

Berriman M, Haas BJ, LoVerde PT, Wilson RA, Dillon GP, Cerqueira GC, Mashiyama ST, Al-Lazikani B, Andrade LF, Ashton PD, Aslett MA, Bartholomeu DC, Blandin G, Caffrey CR, Coghlan A, Coulson R, Day TA, Delcher A, DeMarco R, Dijkeng A, Eyre T, Gamble JA, Ghedin E, Gu Y, Hertz-Fowler C, Hirai H, Hirai Y, Houston R, Ivens A, Johnston DA, Lacerda D, Macedo CD, McVeigh P, Ning Z, Oliveira G, Overington JP, Parkhill J, Pertea M, Pierce RJ, Protasio AV, Quail MA, Rajandream MA, Rogers J, Sajid M, Salzberg SL, Stanke M, Tivey AR, White O, Williams DL, Wortman J, Wu W, Zamanian M, Zerlotini A, Fraser-Liggett CM, Barrell BG, El-Sayed NM (2009). The genome of the blood fluke Schistosoma mansoni. Nature.


2008

McVeigh P, Alexander-Bowman S, Veal E, Mousley A, Marks NJ, Maule AG (2008). Neuropeptide-like protein diversity in phylum Nematoda. International Journal for Parasitology.

Abad P, Gouzy J, Aury JM, Castagnone-Sereno P, Danchin EG, Deleury E, Perfus-Barbeoch L, Anthouard V, Artiguenave F, Blok VC, Caillaud MC, Coutinho PM, Dasilva C, De Luca F, Deau F, Esquibet M, Flutre T, Goldstone JV, Hamamouch N, Hewezi T, Jaillon O, Jubin C, Leonetti P, Magliano M, Maier TR, Markov GV, McVeigh P, Pesole G, Poulain J, Robinson-Rechavi M, Sallet E, Ségurens B, Steinbach D, Tytgat T, Ugarte E, van Ghelder C, Veronico P, Baum TJ, Blaxter M, Bleve-Zacheo T, Davis EL, Ewbank JJ, Favery B, Grenier E, Henrissat B, Jones JT, Laudet V, Maule AG, Quesneville H, Rosso MN, Schiex T, Smant G, Weissenbach J, Wincker P (2008). Genome sequence of the metazoan plant-parasitic nematode Meloidogyne incognita. Nature Biotechnology.


2006

McVeigh P, Geary TG, Marks NJ, Maule AG (2006). The FLP-side of nematodes. Trends in Parasitology.

McVeigh P, Leech S, Marks NJ, Geary TG, Maule AG (2006). Gene expression and pharmacology of nematode NLP-12 neuropeptides. International Journal for Parasitology.


2005

McVeigh P, Leech S, Marks NJ, Geary TG, Maule AG (2005). Neuropeptide signalling systems in flatworms. Parasitology.

McVeigh P, Leech S, Mair GR, Marks NJ, Geary TG, Maule AG (2005). Analysis of FMRFamide-like peptide (FLP) diversity in phylum Nematoda. International Journal for Parasitology.